Feeling Positive?

Is a donor "reactive" for a particular infectious disease marker or is he "positive"? What does "repeat reactive" mean? Can you have a reactive test on a particular sample and still be categorized as "non-reactive"? When studying transfusion-transmitted diseases (podcast on this topic coming soon), you will read terminology that can sometimes be confusing to non-virologists of the world (I proudly include myself in that category!). This blog entry will discuss several confusing terms related to viral marker testing results.

XMRV-An Emerging Infection Case Study

In the early 1980’s, physicians in San Francisco and New York were puzzled by a growing number of aggressive cases of a rare malignancy known as Kaposi’s sarcoma, as well as a rare lung infection, Pneumocystis carinii (now "jirovecii") pneumonia. These illnesses were discovered initially in homosexual men, but were later seen in a growing number of patients suffering from hemophilia.